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Cholesterol-lowering effect of Haritaki

Terminalia Chebula: Cholesterol

Scientific experiments and studies on the cholesterol-lowering effect of Haritaki on the skin.

Haritaki was found to be an excellent agent for lowering lipid levels. Animal studies also showed that animals treated with Haritaki caused a significant reduction in total cholesterol, triglycerides, total protein and an increase in high density lipoprotein cholesterol.

Hypolipidemic activity of haritaki (terminalia chebula) in atherogenic diet induced hyperlipidemic rats

Journal of Advanced Pharmaceutical Technology Research 2010 Apr;1(2):229-35.

Haritaki (Terminalia chebula) family Combretaceae is an important plant used traditionally for medicinal purposes. It is component of the classic Ayurvedic combination called "Triphala". Hyperlipidemia was induced by treated orally with atherogemc diet. In atherogenic diet induced hyperlipidemic model, the rats receiving treatment with Haritaki showed significant reduction in total cholesterol, triglycerides, total protein and elevation of high density lipoprotein cholesterol. Haritaki was found to possess significant hypolipidemic activity. The results also suggest that Haritaki at 1.05 and 2.10 mg/kg b.wt. concentrations are an excellent lipid-lowering agent.

[Link to the scientific study]

Hypocholesterolemic effect of Terminalia chebula fruit (Myrobalan) in mice

Ancient Science of Life . 2004 Apr;23(4):11-5.

Cholesterol fed mice were administered powdered myrobalan, the fruit of Terminalia chebula, to evaluate its antiatherogenic activity. Male mice were fed a diet containing 1% cholesterol with or without myrobalan for 100 days. The cholesterol containing diet fed to mice caused increased food intake, body weight, serum cholesterol, triglyceride, thickening of the walls of aorta and shrinkage in its lumen (group 2) . The oral administration of myrobalan to mice on atherogenic diet successfully reversed these effect (group 3). However, the food intake was observed to be high as compared to the control animals. Control animals (group 1) received only the vehicle. The results suggest that myrobalan has hypocholesterolemic effect in animals fed with atherogenic diet.