- Effects of Haritaki
- Telomere
Potential effects of Haritaki on cell rejuvenation
Terminalia Chebula: Telomere
Scientific experiments and studies on the potential cell rejuvenating effect of Haritaki.
A 2004 study suggests that Haritaki extracts may potentially inhibit age-related telomere shortening and UVB-induced oxidative damage in vitro, which indicates that Haritaki could potentially support the lifespan of cells.
At present, there is no scientifically confirmed health benefit of Haritaki recognized by the EFSA (EU Authority for Science, Safe Food, and Sustainability). The described experiences are based on traditional applications and individual reports. The available scientific studies should therefore be evaluated and interpreted individually.
Cytoprotective effect on oxidative stress and inhibitory effect on cellular aging of Terminalia chebula fruit
Source: Phytotherapy Research PTR 2004 Sep;18(9):737-41. doi: 10.1002/ptr.1529Quote from the study: The ethanol extract from the fruit of Terminalia chebula (Combretaceae) exhibited significant inhibitory activity on oxidative stress and the age-dependent shortening of the telomeric DNA length. In the peroxidation model using t-BuOOH, the T. chebula extract showed a notable cytoprotective effect on the HEK-N/F cells with 60.5 +/- 3.8% at a concentration of 50 microg/ml. In addition, the T. chebula extract exhibited a significant cytoprotective effect against UVB-induced oxidative damage. The life-span of the HEK-N/F cells was elongated by 40% as a result of the continuous administration of 3 microg/ml of the T. chebula extract compared to that of the control. These observations were attributed to the inhibitory effect of the T. chebula extract on the age-dependent shortening of the telomere, length as shown by the Southern blots of the terminal restriction fragments (TRFs) of DNA extracted from subculture passages."
[Link to the scientific study]
